Time To Make the Switch: 11 Reasons To Move From Cloning To Gene Synthesis In 2011

Menlo Park, CA
Monday, January 31, 2011

Having trouble with your resolutions list already? Make the switch from cloning to synthesis and give yourself more time and energy to focus on your research. Resolve to work smarter—saving time and money and getting better results.

While you consider all the reasons to make the switch, check out the ever-growing list of leading scientists that have already said goodbye to cloning: Success Stories


1. Save Time—Your PI is tired of waiting

Every day saved in the process of accessing your genetic constructs is a day gained on the competition. First to publish is also first to get the next grant. First to patent is also first to get next VC round. DNA2.0 offers custom synthesized genes up to 1kb in size guaranteed to ship in 5 business days—the fastest possible gene synthesis service available. Our regular service is an industry-leading 8-10 day turnaround.


2. Reliable, High-Protein Expression Yields

No point in getting a synthetic gene if it does not express your protein. Breakthrough research by DNA2.0 has identified the design principles by which codons are used to maximize protein expression. The peer-reviewed, published research, funded by the National Science Foundation, has produced a set of design algorithms that reliably offers maximized expression yields for heterologous protein expression.

3. It’s Never Been More Affordable

It may seem like cloning in-house is “free,” but the truth is that the cost of your lab time adds up. Synthesis now costs less than cloning, and DNA2.0’s prices are more affordable than ever before.

4. Focus on Innovation—Not reading trace files

You’re not in the lab to clone genes, you’re there to do science. Don't spend months fiddling with expression vectors, tags, culture conditions and temperatures. With DNA2.0 maximal protein expression, you can focus on the critical experiments that advance your research.

5. Improve on Nature

Any sequence you can imagine is available with synthetic genes. DNA2.0's rapid and efficient custom gene synthesis allows you to redesign entire gene sequences to maximize the likelihood of high protein expression, easy genetic manipulation, minimal promoter leakiness and convenient protein purification.

6. Avoid Mistakes

Why risk losing time on mistakes that could happen in-house? When you ask DNA2.0 to handle your gene synthesis, we make sure you get the genes you need, every time, on time. Never again curse the Gods of PCR.


7. Instantly Scale Up or Down

You need 1,000 genes today and then nothing for 12 months? You need a simple gene or multisite combinatorial library? No problem. DNA2.0 handles large and small orders with equal efficiency. No need to scale your in-house molecular biology resources to fit the ups and down of your research.


8. Ph.D.-level Support

Instant access to expertise in the fields of protein expression, gene synthesis and the voodoo of cloning. We at DNA2.0 have published extensively in the area of technology development and new applications of synthetic biology. DNA2.0 is a resource and research partner for accurate and innovative, useful solutions. Let our Ph.Ds be an extension of your lab.

9. Airtight IP Protection

DNA2.0 understands the value of your intellectual property. DNA2.0 never outsources your gene synthesis orders to facilities in countries with lax IP protection. DNA2.0 synthesizes all orders at our state-of-the-art facility in Menlo Park, California.

10. Groundbreaking Gene-Design Tool—Free!

What could be easier than using DNA2.0‘s patented drag-and-drop sequence functionality to design genes de novo? DNA2.0's free Gene Designer enables you to put your imagination to work and guides you through every step, from inspiration to synthesized gene. With a tool like Gene Designer doing the heavy lifting, you spend more time focused on your research.


11. Freedom of Expression with the pJexpress family of vectors

DNA2.0 synthetic genes are available in vectors that are immediately usable for bacterial and mammalian protein expression. Cloning into these vectors is free of charge and the constructs are provided without IP restrictions.

Make the leap to synthesis in 2011.

This is the one resolution that will help you succeed with the all the rest on your list. DNA2.0 has provided tens of thousands of genes to thousands of customers, synthesizing many millions of base pairs. It is by far the most published synthetic gene vendor, providing expert support to and collaborations with scientists. DNA2.0 guarantees researchers high quality synthetic genes, delivered on time, every time.

Call or email today for a quote: info@DNA20.com or toll free at +1 877 DNA TOGO.


About DNA2.0, Inc.

Founded in 2003, DNA2.0 is the leading synthetic biology company. It is the fastest provider of synthetic genes, based in the US with a global customer base encompassing academia, government and the pharmaceutical, chemical, agricultural and biotechnology industries. DNA2.0 explores novel applications for synthetic genes and is exploiting the synergy between highly efficient gene synthesis process and new protein optimization technologies. The tools and applications brought to market by DNA2.0 are transforming biology into an engineering discipline. The company is privately held and is headquartered in Menlo Park, Calif.

For more information, please visit www.DNA20.com or email Claes Gustafsson, VP Sales cgustafsson@DNA20.com.