DNA2.0 Integrates Synthetic Biology Open Language (SBOL) Into Gene Designer
First Standardized Information Exchange Framework for Synthetic Biology Enables Sharing and Storage of Computer-Designed DNA Sequences
DNA2.0 the leading provider of bioengineering solutions, today announced the integration of the Synthetic Biology Open Language (SBOL) into the company's groundbreaking gene design and assembly tool, Gene Designer. SBOL is a synthetic biology standard exchange format that allows scientists to share, store, explore and publish genetic elements created through computer design. This newly-released language forms the basis for Gene Designer's integration of genetic parts from BIOFAB and enables a new feature in the application called Diagram. Diagram provides a clean visualization interface of designed sequences and eases scientific collaboration by enabling graphic exports of sequences.
Biological design tools such as Gene Designer are playing a key role in the evolution of biology from a discovery-based science to an engineering discipline, where individuals from diverse technical backgrounds interact with genetic information. In order to make these tools more efficient between scientists and across disciplines, it is critical that companies, labs and individual scientists are able to share and store hierarchical sequence information in a format that is consistent, stable and accurately annotated. SBOL is the first such standardized information exchange framework created specifically for bioengineering. SBOL's development began in 2008 with a small grant from Microsoft, and since then it has grown to include a wide consortium of individuals, public institutions and commercial enterprises both in the US and Europe. SBOL version 1.0 was released in October, 2011.
"Only through the integration of standardized, open source tools and datasets from the public domain with the emerging synthetic biology industry will we be able to build the framework for the next manufacturing revolution: bioengineering. I'm excited to see the early adoption of SBOL and BIOFAB by DNA2.0 with their Gene Designer program. The ability to create, share and utilize standardized high quality biological building blocks is key to the advancement of synthetic biology" said BIOFAB Director Drew Endy, of Stanford Bioengineering and the BioBricks Foundation."
DNA2.0 developed the free software application, Gene Designer, to help scientists create genes with a graphically rich computer-aided design tool that enables bioengineers to easily manipulate and visualize DNA elements such as promoters, terminators, fusion tags and vector components. Gene Designer's SBOL compliance, along with the new Diagram feature, makes it easier than ever for scientists to share accurate, consistent sequence data across any enterprise. DNA2.0 is committed to ensure full SBOL compatibility as the field of bioengineering and synthetic biology grows.
"The growth of the bioengineering industry enabled by synthetic biology and gene synthesis requires a new software platform for interacting with designed genetic information," said Alan Villalobos, Director of Synthetic Biology at DNA2.0. "We are proud to be part of the SBOL development team that is building the first industrial framework for bioengineering."
DNA2.0 is the leading bioengineering solutions provider. Founded in 2003, DNA2.0 offers an integrated pipeline of solutions for the research community, including gene design, optimization, synthesis and cloning, as well as platforms for protein and strain engineering. It is the fastest provider of synthetic genes—based in the US with a global customer base encompassing academia, government and the pharmaceutical, chemical, agricultural and biotechnology industries. DNA2.0 is by far the most published synthetic gene vendor, providing expert support to and collaboration with scientists. DNA2.0 explores novel applications for synthetic genes and is exploiting the synergy between highly efficient gene design and synthesis processes and new protein optimization technologies. DNA2.0's tools and solutions are fueling the transformation of biology from a discovery science to an engineering discipline. The company is privately held and is headquartered in Menlo Park, Calif. For more information, please visit www.DNA20.com.