Gene synthesis and bioengineering company DNA2.0 Inc. today announced that the United States Patent and Trade Office has issued U.S. Patent No. 8,975,042 covering the unique technology created by DNA2.0 scientists for synthetic fluorescent and colored proteins and the methods for using them.
Fluorescent and colored proteins are a critical tool in contemporary bioscience, allowing the rapid and convenient observation of protein expression and interaction. DNA2.0’s IP-Free© synthetic non-Aequorea fluorescent and colored proteins covering the full spectrum are an ideal source of protein coding sequences that can be easily cloned into any expression vector of choice for use as positive controls, monitoring of protein expression, and a plethora of other applications.
“We are extremely excited to offer the scientific community an IP-Free palette of synthetic fluorescent and colored proteins.” said Claes Gustafsson, DNA2.0’s Chief Commercial Officer. “Our ProteinPaintbox® technology is a valuable tool for research, with uses ranging from reporters in transgenic systems to biosensors.”
Several unique proteins of each color have been created to cover a range of spectra and optimized for a variety of host systems including bacterial, mammalian and yeast. In addition, orthogonal co-expression of two different colors in a single host allows scientists to follow multiple processes simultaneously. DNA2.0 currently offers fluorescent proteins in Cyan (CFP), Green (GFP), Orange (OFP), Red (RFP), and Yellow (YFP). DNA2.0 colored proteins include Blue, Magenta, Orange, Pink, Purple, Teal and Violet. A subset of the Paintbox proteins has been contributed to the public domain via the BioBrick Public Agreement. DNA2.0’s ProteinPaintbox® is available without intellectual property restrictions, for the Synthetic Biology community to improve upon and to incorporate into innovative products.
About DNA2.0:
DNA2.0 is the leading bioengineering solutions provider, offering an integrated pipeline of solutions including gene design, optimization and synthesis, expression vectors, and platforms for protein and strain engineering. DNA2.0 explores novel applications for synthetic genes and the synergy between efficient gene design and protein optimization technologies. DNA2.0’s tools and solutions are fueling the transformation of biology from a discovery science to an engineering discipline. Visit http://www.DNA20.com.