Difficult to Express Proteins
Achieve improved expression levels of your protein with optimized vectors, codon optimization, and protein engineering.
ATUM utilizes a proprietary machine learning driven platform, GPS™ technology, to explore multidimensional sequence space helping clients optimize nucleotide, amino acid, expression vector, and genome sequence elements.
Using the GPS™ platform, ATUM explores optimized DNA sequences with customer optimized environmental conditions to identify ideal conditions for custom outputs.
Case Study 1: Improved GPCR Expression combining Vectorology + Codon Optimization
- Matrix of 48 vectors and 3 different codon optimized variants of the gene
- Screened in HEK, CHO, and other mammalian cell-lines
“Multi Dimensional Engineering” image, derivative of work by Alex
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